「中耳炎になりやすい子に十全大補湯が有効」
十全大補湯服用で急性中耳炎、発熱期間、抗菌薬使用、病院受診、
救急受診のいずれも減る。投与中止すると急性中耳炎の頻度が増
し、再び投与すると急性中耳炎が減る。これを使うと鼻の吸引も
不要、通院不要、親子そろってラクチン。
２歳の女児。秋から春先にかけてドロドロの鼻水。中耳炎も繰り返す。
その都度、耳鼻科で抗菌薬。それでも耳漏が止らない日々が続いた。
この１０月から十全大補湯を服用。２日後からピタっとドロ鼻が止り、
夜間睡眠時も鼻呼吸でＯＫ。その子が通う保育園では風邪が蔓延
してる。その中で鼻がすっきりしてるのは、十全大補湯飲んでる子だけ。
Effects of Japanese herbal medicine, Juzen-taiho-to, in otitis-prone
children - a preliminary study
Authors: Yumiko Maruyama a; Shigeru Hoshida a; Mitsuru Furukawa b;
Makoto Ito b
Affiliations: a Kurobe City Hospital, Kurobe, Japan
b Department of Otolaryngology-Head and Neck Surgery, Division of
Neuroscience, Kanazawa University Graduate School of Medical Science,
Kanazawa, Japan
Acta Otolaryngol. 2008 Jun 12:1-5.
PMID: 18608005 [PubMed - as supplied by publisher]
【Abstract】
Conclusion: Juzen-taiho-to (JTT, TJ-48), a Japanese herbal medicine
that improves immune function, was found to be effective in otitis-prone
in children.
Objective: To evaluate the efficacy of JTT against intractable and
recurrent infections in immature immune systems, we administered
JTT to otitis-prone infants and investigated clinical changes before
and during JTT administration.
Subjects and methods: Twenty-four otitis-prone infants were administered
JTT at 0.10-0.14 g/kg/day twice a day for 3 months. We compared clinical
course, such as frequency of acute otitis media (AOM), duration of fever
and antibiotics administration, and hospital visits for the periods before and
during JTT administration.
Results: Medication compliance rate was 87.5%, and administration of
JTT led to remission in 95.2% patients. No apparent side effects were
observed. The frequency of AOM decreased significantly (Wilcoxon
signed rank test, p=0.000) with JTT. The duration of fever (p=0.000)
and administration of antibiotics (p=0.001), as well as the number of
hospital visits (p=0.001) and emergent hospital visits (p=0.000) showed
significant decreases after JTT administration. After the end of the JTT
period, 14 of 21 (66.7%) patients started to take it again, as they
experienced purulent otitis media and/or other infections after
discontinuation. The frequency of AOM increased significantly after
stopping JTT (p=0.004) and decreased again with JTT resumption (p=0.005).
